MOFFITT AM REPORT PEARLS 8/10/16: Eosinophilic Meningitis!

Thanks to Tim for presenting a fascinating and sad case involving multiorgan failure and CSF pleocytosis. Special thanks also to Nicole Rosendale for being our neurology guest consultant for the morning!


Today’s Top Pearl: Only multicellular parasites (worms and flukes) should cause an eosinophilic meningitis; unicellular parasites (e.g. amoeba) should not.


For those interested in more detail:

See this prior blog post for the ddx of multiorgan dysfunction:


Categories of disease to consider for eosinophilic meningitis:


  • Multicellular parasites (worms and flukes)
  • Fungal: Cocci
  • Atypical bacterial/mycobacterial: TB, syphilis, RMSF
  • Viral: Coxsackie, LCMV
  • Malignancy (lymphoma, myeloprolifrative neoplasm aka. Hypereosinophilic syndrome)
  • Infiltrative disease (sarcoid)
  • Vasculitis
  • Medications

From a 2013 review recommended by Harry for the ddx of eosinophilic meningitis:

Pic 1.png

And here’s a nasty pic of some WERMS!!

Pic 2

Adult A. cantonensis. Male is on the left, female on the right. Cue romantic music.






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