Take-home point from daily ditty: for secondary hypogonadism (low testosterone and low FSH and LH), rule out prolactinemia and hemochromatosis!!
- For most patients this is isolated to the skin with some arthralgias and is a self-limited diseas
- Predominantly involves the skin but can also affect other organs (lungs, kidney, GI)
- Hypocomplementemia can be associated with extensive vasculitis and systemic features
- Commonly idiopathic but can be associated with autoimmune disease, drug reactions, infections, or malignancy
- Treatment: anithistamines (for pruritus), NSAIDs for arthralgias.
- If moderate, can add steroids with dapsone or colchicine.
- If severe or refractory with end organ or life-threatening disease, can use mycophenolate mofetil, MTX, azathioprine, cyclosporine
Approach to Urticaria
And, in my search for more approaches to rashes, here is one based on morphology: